Pox outbreaks in Sheep and Goats at Makhdoom (Uttar Pradesh), India: Evidence of Sheeppox Virus Infection in Goats

Bhanuprakash, V. and Venkatesan, G. and Balamurugan, V. (2010) Pox outbreaks in Sheep and Goats at Makhdoom (Uttar Pradesh), India: Evidence of Sheeppox Virus Infection in Goats. Transboundary and Emerging Diseases, 57 (5). pp. 375-382.

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Abstract

Sheeppox and goatpox outbreaks occur often in India incurring huge economic loss to the small ruminant industry. This paper describes two sheeppox outbreaks, of which one occurred in an organized sheep breeding farm at Makhdoom (Uttar Pradesh), India, during 2007 and another in goats at the Central Institute of Research on Goats, Makhdoom (Uttar Pradesh), India during 2008. In the first outbreak, a local Muzaffarnagari sheep breed was affected (n = 477) with morbidity and mortality rates, respectively, of 100% and 53.9% accompanied by significant productivity losses. In the 2008 outbreaks, a small number of goats were affected without any mortality. The tissue and swabs collected from both the outbreaks were processed and inoculated onto Vero cells, and the causative agent of the outbreaks, capripox virus (CaPV), was isolated. The identity of the virus was confirmed as CaPV based on electron microscopy, experimental pathogenesis in sheep, capripox-specific conventional and real-time PCRs. Sequence analysis of the P32 envelope protein gene revealed that the causative agent of both outbreaks was confirmed as sheeppox virus (SPPV) implying SPPV infection not only in sheep but also goats in India

Item Type: Article
Additional Information: This study was supported by grants from the Ministry of Forest and Environment (MOFE), Government of India, under the All India Coordinated Project on the Taxonomy capacity building of poxviruses (AICOPTAX).
Uncontrolled Keywords: Sheeppox; Outbreak; Isolation; Pathogenesis; Electron Microscopy; Polymerase chain reaction; Sequencing
Author Affiliation: Poxvirus Disease Laboratory, Division of Virology, Indian Veterinary Research Institute, Mukteswar, Nainital (District) Uttarakhand, India
Subjects: Animal Husbandary
Divisions: General
Depositing User: Ms Ishrath Durafsha
Date Deposited: 25 Jun 2014 03:59
Last Modified: 25 Jun 2014 03:59
Official URL: http://dx.doi.org/10.1111/j.1865-1682.2010.01158.x
URI: http://eprints.icrisat.ac.in/id/eprint/13272

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