Comparative safety assessment for biotech crops

Kok, E.J. and Kuiper, H.A. (2003) Comparative safety assessment for biotech crops. Trends in Biotechnology, 21 (10). pp. 439-444.

[img] PDF
Restricted to ICRISAT researchers only


Since the first discussions on strategies to assess the food safety of genetically modified (GM) crop plants, assessment of GM plants and derived tissues has been based on comparisons with their traditionally bred counterparts. This was termed the Principle of Substantial Equivalence. However, implementation of the principle led to controversy and hampered the precision of the actual safety assessment. Here, we propose the principle be rephrased into the Comparative Safety Assessment strategy. This describes the analytical nature of the first step of the entire (GM) food safety assessment in combination with consecutive toxicological and nutritional evaluations. Further development of advanced analytical methods will help to improve the efficacy of assessment strategies.

Item Type: Article
Author Affiliation: RIKILT Institute for Food Safety, Bornsesteeg 45, PO Box 230, 6700 AE, Wageningen, Netherlands
Subjects: Crop Improvement > Genetics/Genomics
Crop Improvement > Plant Breeding
Crop Improvement > Biotechnology
Divisions: Other Crops
Depositing User: Sandhya Gir
Date Deposited: 19 Oct 2010 06:11
Last Modified: 21 Oct 2010 03:23
Official URL:

Actions (login required)

View Item View Item