RNA-Seq: a revolutionary tool for transcriptomics

Wang, Z. and Gerstein, M. and Michael, S. (2009) RNA-Seq: a revolutionary tool for transcriptomics. Nature Reviews Genetics, 10 (1). pp. 57-63.

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RNA-Seq is a recently developed approach to transcriptome profiling that uses deep-sequencing technologies. Studies using this method have already altered our view of the extent and complexity of eukaryotic transcriptomes. RNA-Seq also provides a far more precise measurement of levels of transcripts and their isoforms than other methods. This article describes the RNA-Seq approach, the challenges associated with its application, and the advances made so far in characterizing several eukaryote transcriptomes

Item Type: Article
Author Affiliation: Department of Molecular, Cellular and Developmental Biology, Yale University, 219
Subjects: Plant Production > Production Practices
Divisions: General
Depositing User: Syamala
Date Deposited: 11 May 2011 05:03
Last Modified: 11 May 2011 05:03
Official URL: http://dx.doi.org/10.1038/nrg2484
URI: http://eprints.icrisat.ac.in/id/eprint/2008

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