Further studies of the goitrogenic effects of pearl millet diets

Klopfenstein, C.F. and Hoseney, R.C. and Leipold, H.W. (1983) Further studies of the goitrogenic effects of pearl millet diets. Nutrition Reports International, 28 (5). pp. 1137-1144.

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In some parts of Africa there is a strong positive correlation between incidence of goitre and millet production per capita. For 6 weeks groups of about 10 male Wistar rats were given a diet of whole grain (13.8% protein) pearl millet meal without or with potassium iodide 30 μg/g drinking water, autoclaved millet meal, or sorghum grain meal without or with iron 200 μg/g drinking water. Rats given millet meal ceased to gain weight after the fourth week and they developed signs similar to those of colloid goitre in man. Autoclaving the grain seemed to alleviate the signs, but the iodine supplement did not. Changes in thyroid hormone values could not be attributed to high intake of Fe, but Fe intake could have been associated with certain histological changes in the thyroid. Initially millet was a more efficient feed than sorghum, but after 6 weeks sorghum was the more efficient feed.

Item Type: Article
Author Affiliation: Department Grain Science and Industry, Kansas State University Manhattan
Subjects: Plant Protection
Postharvest Management
Divisions: Millet
Depositing User: Mr. SanatKumar Behera
Date Deposited: 18 May 2012 05:14
Last Modified: 18 May 2012 05:14
URI: http://eprints.icrisat.ac.in/id/eprint/5459

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