Antiaflatoxigenic activity of eugenol is due to inhibition of lipid peroxidation

Jayashree, T. and Subramanyam, C. (1999) Antiaflatoxigenic activity of eugenol is due to inhibition of lipid peroxidation. Letters in Applied Microbiology, 28 (3). pp. 179-183.

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Eugenol (4-allyl-2-methoxy phenol) inhibited aflatoxin production by Aspergillus parasiticus NRRL 2999 in a dose-dependent manner up to a concentration of 0.75 mmol/litre without inhibiting growth. When the mould was grown for 3 days in the presence of 0.45 mmol/l eugenol (concentration inhibiting aflatoxin production by 50%), in vivo activities of components of polysubstrate monooxygenase were decreased at idiophase, concomitant with decreased activities of enzymes involved in free radical scavenging, lipid peroxidation and maintenance of redox potential. These results indicated that antiaflatoxigenic actions of eugenol may be related to inhibition of the ternary steps of aflatoxin biosynthesis involving lipid peroxidation and oxygenation.

Item Type: Article
Additional Information: SNNigam Collection
Author Affiliation: Department of Biochemistry, University College of Science, Osmania University, Hyderabad 500 007, AP, India.
Subjects: Plant Protection
Statistics and Experimentation > Experimentation
Plant Physiology and Biochemistry > Biochemistry
Divisions: General
Depositing User: Mr Balakrishna Garadasu
Date Deposited: 02 Apr 2013 04:47
Last Modified: 02 Apr 2013 04:47
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